Well the only thing that REALLY matters about the temp is whether or not u are safely cooking the meat.
If you smoke a chicken, meat loaf, or an uncured sausage/lunch meat type item and u put on 180F and it takes 10 hours to hit 140-160F Internal Temp (IT) then I would be very wary that u basically created a botulism or salmonella bombs lol.
If you are smoking something with little to no safety risk like a cured item then there is no issue with going 180F vs 225F.
As long as u can be safe u can start as low as u like. I do my chicken wings really low temp like 180-190 for a couple of hours and then finish them on the grill to actually cook them and to get the skin right. This is safe cause I get that chicken to safe internal temps well before the general 4 hour guideline.
Other things to consider with temp are the following:
- Chicken/Turkey skin comes out like leather or rubber if not cooked at a high enough temp. I find 325F to always give edible skin. Others go lower but I havent had much CONSISTENT luck unless my smoker is at 315-325F cooking temp or above.
- Briskets and pork butts and ribs don't really care what temp you cook/smoke them at. So i go 275F to finish faster. If i could go higher i would but i dont wanna stress the insulation in my rewired MES unit since the insulation is probably not rated much over 300F.
- With a pellet grill/smoker, the lower your temp the more smoke u get. This is just the way fire and smoke works. If you want more smoke with higher temps in this situation then many people use a pellet smoker tube to generate additional smoke separate from what the pellet grill is producing while burning the pellets for heat.
- If something cooks fast like boneless skinless chicken breast then lowering the temp to get more smoke time is something to consider.... again as long as the meat is cooked within a safe time period. I can smoke boneless skinles chicken breast in like an hour and a half but I turn the smoker down low to get at least 2-2.5 hrs of smoke on them so I balance the heat vs amount of smoke in such a case.
I hope this info helps and Im sure others will chime in on what safe vs not safe as I have intentially not covered every case under the sun. My intent was to raise the awareness so u can go from there and the safety needed depending on what u are smoking as different meats and different approaches (cured vs not) lead to different safety practices :)