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No mule experience here... but someone surly does. Stop into the Roll Call forum and give us an intro... your experience, smoker type etc. It's just polite, and we're nosy that way :{) Welcome to SMF!
Copied from my welcome post in Roll Call:
Now..I DO have Whitetail experience. I rubbed the front shoulder down with rendered bacon grease, shook on my rub, and used some more grease in my standard mopping sauce for it. Came out VERY moist and tender... as PORK FAT RULES!
i've got a friend in tennessee who does it this way (see link below). i am sure that if your equipment, preferences etc. are a bit different, they can be adapted from the basic method he describes:
some good advice already. last fall i got a venison ham kit from a processor supply and cured a whole deer quarter. and smoked it. it was really good. i was shocked how close to ham deer could taste.
also you can lard it but placing thin strips of pork fat into the quarter by making thin slits and inserting the fat strips into it. hepls add flavor and keep it moist.