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i usually use the anmps and smoke the whole time,when i do use the chips i add them every30-45 minutes,i smoke the time, some people don't smoke the whole time,you'll have to try some different ways to see what you like the best.
I smoke the whole time myself, I like as much smoke flavor as I can get. The only exception is when I employ the 3-2-1 or 2-2-1 method (which I occasionally do), in which the 1.5-2 hour foil wrap period I just put them in the oven rather than the smoker. So that would be 3 hours on smoke, 2 hours wrapped in foil in oven (or smoker without smoke if you like) and then last 1 hour on smoke.
Smoking time IMO depends on the color and density of the smoke, regardless how it is applied and your personal taste. Learn to keep good notes and you will soon be able to determine how long a certain product should be smoked using any smoker or smoke generator.