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Some people spray, some don't. For your first time I would suggest you spray. Next time don't and see which way you like better. A lot of people use a mix of apple juice and rum to spray with. Straight apple juice would work fine also.
Ok sounds good I got a large rack of spare ribs and a rack of baby back ribs. Will the babyback good faster I have read different things. I am trying to prove my wife wrong and not screw this up.
If you want to "impress" the wife (and keep it on the safe side) use the 3-2-1 method. 3 hours unwrapped, 2 hours wrapped with a sprinkel of apple juice, 1 hour unwrapped to firm them back up. It produces fall off the bone tender ribs and is a very foregiving method
i've gotten to the point where i only spray if i am already fiddling around (putting in wood, turning meat etc.); having said that, i do beleive it is a necessary step.
whatever you do, don't spray until 2 hours into the smoke or you will spray your rub off.
i would also suggest adding a little bit of some kind of oil to the spray. it doesn't ahve to be much - i add about 1/4 to 1/3 cup of olive oil to 2 cups of mop and have had no problems. i've also used melted butter with a little olive oil to help emulsify it into the mop and keep from clumping.